Ixcela

How does Ixcela Biome Support specifically support athletes?

What makes a great probiotic?

It’s the number of strains + CFUs. Most probiotics only include a few strains of bacteria. Ixcela’s Biome Support is not only one of the most diverse probiotics on the market, but it’s formulated to include bacteria strains that actually support your active lifestyle as well.

Here’s why Ixcela Biome Support is runners and triathlete’s favorite performance probiotic


Read the full label here

Ixcela’s Biome Support has a combination of 17 powerful bacterial strains that have been proven to help with the most common health struggles that athletes face, making it the perfect probiotic for runners and triathletes looking to gain an edge.

  • Improve athletic endurance

  • Reduce fatigue, pain, and inflammation

  • Improve sleep and recovery

  • Reduce gut symptoms

  • Improve immune functions

  • Improve mood and sense of wellbeing

  • Increase muscle strength

  • Increase metabolism and energy levels

$109.99 for a 90-day supply

The 17 strains listed below are all included in Ixcela Biome Support.

  1. Bifidobacterium bifidum (B. bifidum)

    • Improves immune functions as shown in improved immunological markers

    • Reduces incidence of upper respiratory tract symptoms (URTS)

    • Reduces the number of days (duration) with URTS

    • Reduces incidence of GI symptoms (GIS)

    • Reduces the number of days (duration) with GIS

    • Increases gut barrier function

    • Promotes vitamin synthesis

    • Improves insulin concentration

    • Improves maximum oxygen output

    • Improves or maintains good sleep quality, including during increased stress

    • Reduces muscle pain and soreness

    • Anti-inflammatory as shown in reduced inflammation markers

  2. Bifidobacterium breve (B. breve)

    • Increases antioxidants in blood - reduces oxidative stress

    • Anti-inflammatory as shown in inflammation markers

    • Regulates inflammation after exercise to enhance muscle regeneration

    • Involves in signaling pathways that promote muscle protein synthesis

    • Increases muscle mass and strength

  3. Bifidobacterium lactis (B. lactis)

    • Improves immune functions as shown in improved immunological markers

    • Reduces incidence of upper respiratory tract symptoms (URTS)

    • Reduces incidence of GI symptoms (GIS)

    • Increases gut barrier function

    • Improves or maintains good sleep quality, including during increased stress

    • Reduces muscle pain and soreness

    • Improves GI symptoms

  4. Bifidobacterium infantis (B. infantis)

    • Improves immune functions as shown in improved immunological markers

    • Increases antioxidants in the blood, reduces oxidative stress

    • Anti-inflammatory as shown in inflammation markers

    • Reduces stress symptoms

    • Improves reported mood and sense of well-being

  5. Bifidobacterium longum (B. longum)

    • Improves immune functions as shown in improved immunological markers

    • Reduces incidence of upper respiratory tract symptoms (URTS)

    • Reduces the number of days (duration) with URTS

    • Reduces incidence of GI symptoms (GIS)

    • Reduces the number of days (duration) with GIS

    • Promotes vitamin synthesis

    • Increases antioxidants in the blood, reduces oxidative stress

    • Anti-inflammatory as shown in inflammation markers

    • Reduces stress symptoms

    • Improves reported mood and sense of well-being

    • Reduces blood levels of lactate and ammonia after exercise

    • Increases time of exercise to exhaustion

    • Faster recovery time after exercise reported

    • Reduces exercise-induced fatigue

    • Optimizes aerobic energy metabolism

    • Increases muscle mass and strength

    • Improves exercise performance

    • Improves endurance exercise capacity

  6. Lactobacillus acidophilus (L. acidophilus)

    • Improves immune functions as shown in improved immunological markers

    • Reduces incidence of upper respiratory tract symptoms (URTS)

    • Reduces the number of days (duration) with URTS

    • Reduces incidence of GI symptoms (GIS)

    • Reduces the number of days (duration) with GIS

    • Increases gut barrier function

    • Reduces endotoxin levels

    • Improves insulin concentration

    • Improves maximum oxygen output

    • Improves or maintains good sleep quality, including during increased stress

    • Reduces muscle pain and soreness

    • Increases antioxidants in blood, reduces oxidative stress

    • Improves GI symptoms

    • Reduces stress symptoms

    • Faster recovery time after exercise reported

    • Reduces exercise-induced fatigue

    • Optimizes aerobic energy metabolism

    • Reduces number and severity of respiratory illness

    • Improves immune strength in fatigue athletes

    • Increased ATP releases

  7. Lactobacillus brevis (L. brevis)

    • Improves immune functions as shown in improved immunological markers

    • Reduces incidence of upper respiratory tract symptoms (URTS)

    • Increases gut barrier function

  8. Lactobacillus bulgaricus (L. bulgaricus)

    • Improves maximum oxygen output

    • Anti-inflammatory as shown in inflammation markers

    • Reduces incidence of upper respiratory tract symptoms (URTS)

    • Reduces the number of days (duration) with URTS

  9. Lactobacillus casei (L. casei)

    • Improves immune functions as shown in improved immunological markers

    • Reduces incidence of upper respiratory tract symptoms (URTS)

    • Reduces incidence of GI symptoms (GIS)

    • Improves insulin concentration

    • Improves or maintains good sleep quality, including during increased stress

    • Reduces muscle pain and soreness

    • Increases antioxidants in the blood, reduces oxidative stress

    • Anti-inflammatory as shown in inflammation markers

    • Reduces stress symptoms

    • May improve exercise performance

    • Suppresses joint inflammation

    • Reduces joint pain

    • Suppresses cartilage tissue degradation

    • Improves exercise (running) endurance

  10. Lactobacillus helveticus (L. helveticus)

    • Improves immune functions as shown in improved immunological markers

    • Reduces incidence of upper respiratory tract symptoms (URTS)

    • Reduces the number of days (duration) with URTS

    • Reduces incidence of GI symptoms (GIS)

    • Reduces stress symptoms

    • Improves reported mood and sense of well-being

  11. Lactobacillus paracasei (L. paracasei)

    • Increases antioxidants in the blood, reduces oxidative stress

    • Anti-inflammatory as shown in inflammation markers

    • Improved recovery from exhaustive exercise

    • Increased after-meal protein peak concentration, when taken together with yellow pea protein (note for vegan athletes)

  12. Lactobacillus plantarum (L. plantarum)

    • Reduces incidence of upper respiratory tract symptoms (URTS)

    • Reduces incidence of GI symptoms (GIS)

    • Improves or maintains good sleep quality

    • Reduces muscle pain and soreness

    • Increases antioxidants in blood, reduces oxidative stress

    • Anti-inflammatory as shown in inflammation markers

    • Reduces blood levels of lactate, urea nitrogen, and ammonia after exercise

    • Improved recovery from exhaustive exercise

    • Faster recovery time after exercise reported

    • Reduces exercise-induced fatigue

    • Increases blood level glucose levels after exercise

    • Increases muscle mass and strength

    • May improves exercise performance

    • Improves endurance performance

    • Improves endurance exercise capacity

    • Increases serotonin synthase

    • Reduces blood creatine kinase level (reduces muscle damage after exercise)

    • Improves iron and calcium status by enhancing bioavailability

    • Increased ATP releases

    • Improves reported mood and sense of well-being

    • Greater exercise capacity in the days following a triathlon event

    • Reduces bone loss

    • Important for carbohydrate and amino acids metabolisms

  13. Lactobacillus rhamnosus (L. rhamnosus)

    • Improves immune functions as shown in improved immunological markers

    • Reduces incidence of upper respiratory tract symptoms (URTS)

    • Reduces incidence of GI symptoms (GIS)

    • Improves or maintains good sleep quality

    • Reduces muscle pain and soreness

    • Increases antioxidants in the blood, reduces oxidative stress

    • Reduces stress symptoms

    • Improved recovery from exhaustive exercise

    • Reduced GI symptoms after a marathon

    • Reduces stress-induced corticosterone

    • Reduced tender and swollen joints

  14. Lactobacillus salivarius (L. salivarius)

    • Improves immune functions as shown in improved immunological markers

    • Optimizes aerobic energy metabolism

    • Increases muscle mass and strength

    • Improves endurance exercise capacity

    • Reduces blood lactate levels after exercise

  15. Lactobacillus gasseri (L. gasseri)

    • Improves immune functions as shown in improved immunological markers

    • Reduces incidence of upper respiratory tract symptoms (URTS)

    • Reduces the number of days (duration) with URTS

    • Reduces incidence of GI symptoms (GIS)

    • Reduces the number of days (duration) with GIS

    • Improves or maintains good sleep quality

    • Reduces stress (especially exercise-induced stress) symptoms

    • Improves reported mood and sense of well-being

    • Reduces exercise-induced fatigue

    • Facilitates recovery from physical fatigue

    • Improves recovery from mental fatigue

    • May contribute to the maintenance of mitochondria function

  16. Lactobacillus lactis (L. lactis)

    • Reduces incidence of upper respiratory tract symptoms (URTS)

    • Increases gut barrier function

    • Anti-inflammatory as shown in inflammation markers

    • Increases serotonin synthase

  17. Streptococcus thermophilus (S. thermophilus)

    • Improves immune functions as shown in improved immunological markers

    • Reduces incidence of upper respiratory tract symptoms (URTS)

    • Reduces the number of days (duration) with URTS

    • Reduces incidence of GI symptoms (GIS)

    • Improves maximum oxygen output

    • Improves or maintains good sleep quality

    • Reduces muscle pain and soreness

    • Anti-inflammatory as shown in inflammation markers

    • Regulates inflammation after exercise to enhance muscle regeneration

    • Involves in signaling pathways that promote muscle protein synthesis

    • Increases serotonin synthase

What is a probiotic?

Probiotics consist of live, beneficial bacterial microorganisms that can help repopulate the gut microbiome, especially after insult from antibiotics, stress, or poor diet. Ideally, probiotic supplements consist of a variety of different families (strains) of bacteria and/or yeasts. It is also important to have enough of these bacteria, which is why at least 25 billion colony-forming units (CFU) is recommended. Ixcela Biome Support has 30 billion CFU.

Did you know that not all probiotics are created equal? Find out what makes a good probiotic and why Ixcela’s Biome Support Probiotic stands apart from the rest!


What is a prebiotic?

Prebiotics serve as food for bacteria and can help them grow and thrive. The human body is not capable of digesting FOS and inulin fibers; however, bacteria can use the fibers as a substrate (food source) to live on. These same fibers can also assist in keeping bowels regular.

Citations

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  • Miles MP. Probiotics in sports nutrition, chapter 14, “Probiotics. Advanced Food and Health applications” Adriano Brandelli (ed.) Elsevier (2022) 277-295. doi.org/10.1016/B978-0-85170-100024-5

  • Sales KM & Reimer RA (2022) Unlocking a novel determinant of athletic performance: The role of the gut microbiota, short-chain fatty acids, and “biotics” in exercise. J Sport and Health Sci. doi.org/10.1016/j.jshs.2022.09.002

  • Severo JS et al (2022) Probiotics in sports and physical exercise, chapter 14, “Probiotics for Human Nutrition in Health and Disease” de Souza, EL, et al (eds.) Elsevier (2022) 345-372. doi.org/10.1016/B978-0-323-89908-6.00023-6

  • Harnett JE, et al (2021) Probiotic supplement elicit favourable changes in muscle soreness and sleep quality in rugby players. J Sci and Med in Sport 24:195-199 doi.org/10.1016/j.sams.2020.08.005

  • Lee M, et al (2021) Effectiveness of human-origin Lactobacillus plantarum PL-02 in improving muscle mass, exercise performance and anti-fatigue. Scientific Reports (2021) 11:19469. doi.org/10.1038/s41598-021-98958-x

  • Lee M, et al (2021) Lactobacillus plantarum TWK10 improve muscle mass and functional performance in frail older adults: a randomized, double-blind clinical trial. Microorganisms 9:1466. doi.org/10.3390/microorganisms9071466

  • Tavakoly R, et al (2021) Effect of probiotic consumption on immune response in athletes: a meta-analysis. Int J Sports Med 42:769-781. doi.org/10.1055/a-1463-3303

  • Przewlocka K et al (2020) Gut-muscle axis exists and may affect skeletal muscle adaptation to training. Nutrients (2020) 12:1451. doi.org/10.3390/nu12051451

  • Antoni C, et al (2019) Metabolomics and proteomics as tools to advance the understanding of exercise responses: The emerging role of gut microbiota in athlete health and performance. Chapter 19, “Sports, Exercise, and Nutritional Genomics: Current Status and Future Directions” Barh D and Ahmetov I (eds). Elsevier (2019) 433-459. doi.org/10.1016/B978-0-12-816193-7.00019-1

  • Maia LP, et al (2019) Effects of probiotic therapy on serum inflammatory markers: a systemic review and meta-analysis. J Functional Foods (2019) 54:466-478. doi.org/10.1016/j.jff.2019.01.051

  • Nishihira J (2019) The role of probiotics in sports: Application of probiotics to endurance exercise. chapter 36, “Nutrition and Enhanced Sports Performance, Second Edition” Bagchi D (ed). Elsevier (2019) 423-428. doi.org/10.1016/B978-0-12-813922-6.00036-9

  • Pumpa K ,et al (2019) A novel role of probiotics in improving host defence of elite rugby union athlete: a double blind randomized controlled trial. J Sci and Med in Sport 22 (2019):876-881. doi.org/10.1016/jsams.2019.03.013

  • Sawada D, et al (2019) Daily intake of Lactobacillus gasseri CP2305 relieves fatigue and stress related symptoms in male university Ekiden runners: a double-blind, randomized, and placebo-controlled clinical trial. J Functional Foods. doi.org/10.1016/j.jff.2019.04.022

  • Mach N & Fuster-Botella D (2017) Endurance exercise and gut microbiota: a review. J Sports and Health Sci 6:179-197. doi.org/10.1016/j.jshs.2016.05.001

  • Haywood BA, et al (2014) Probiotic supplementation reduces the duration and incidence of infections but not severity in elite rugby union player. J Sci and Med in Sports 17:356-360. doi.org/10.1016/j.jsams.2013.08.004

  • Vitett L, et al (2013) The gastrointestinal microbiome and musculoskeletal diseases: a beneficial role for probiotics and prebiotics. Pathogens 2:606-626. doi:10.3390/pathogens2040606