Ixcela

Duke University and Ixcela explore the link between the gut microbiome and the cardiovascular system

Ixcela has teamed up with the Department of Psychiatry and Behavioral Sciences at Duke University to explore the link between the gut microbiome and the cardiovascular system.

Sun et al. 'Metal stress-induced left ventricular dysfunction and adverse outcome in ischemic heart disease patients', European Journal of Preventive Cardiology 2017. Sun et al. 'Metal stress-induced left ventricular dysfunction and adverse outcome in ischemic heart disease patients', European Journal of Preventive Cardiology 2017.

REMIT Study

Ixcela has teamed up with the Department of Psychiatry and Behavioral Sciences at Duke University to explore the link between the gut microbiome and the cardiovascular system.

Mental stress–induced myocardial ischemia (MSIMI) is common in patients with clinically stable coronary heart disease (CHD) and is associated with poor outcomes. Depression is a risk factor of MSIMI. The REMIT trial investigates whether selective serotonin re-uptake inhibitor (SSRI) treatment can improve MSIMI.

The REMIT study examines the effect of SSRI on MSIMI in vulnerable patients with CHD and probes some potential underlying mechanisms.