GI Issues + Associated Metabolites

Bloating

Indole-3-acetic acid (IAA)
Indole-3-lactic acid (ILA)
Indole-3-propionic acid (IPA)
Serotonin (SER)

Constipation

Serotonin (SER)
3-methylxanthine (3MX)

Cramping

Indole-3-acetic acid (IAA)
Indole-3-lactic acid (ILA)
Indole-3-propionic acid (IPA)
Serotonin (SER)
3-methylxanthine (3MX)

Diarrhea

Serotonin (SER)

Gas

Indole-3-acetic acid (IAA)
Indole-3-lactic acid (ILA)
Indole-3-propionic acid (IPA)

Intestinal permeability (leaky gut)

Indole-3-propionic acid (IPA)

Ixcela Personalized Solutions

Personalized Solutions for GI Issues

No two plans are the same! In addition to customizing plans based on test results, our dietitians often make tweaks for our clients dealing with GI Issues such as:

  • Removing foods you dislike or are sensitive to
  • Suggesting specific breakfast, lunch, snack, and dinner ideas
  • Adjusting supplement routine and dosages
  • Modifying diets like low FODMAP to simplify getting started
  • Coming up with creative hydration practices
  • Offering coffee alternatives for energy boosts in the afternoon
  • Providing sleep recommendations to increase the quality and quantity of sleep
  • Identifying which restorative practices feel most doable

Case Studies

Primary Symptom: Bloating

Hayden, a pediatric medical resident in his 30s, struggled with daily stomach issues for years. His GI discomfort was amplified when he started training for Ironman 70.3 events, and he decided it was time to try something different.

His Ixcela test results revealed:

  • 3-methylxanthine above optimal
  • Xanthine above optimal

After following his Ixcela plan for 90 days, Hayden experienced:

  • 50% Fewer days with bloating
  • 75% fewer days with diarrhea
  • 71% decrease in post-race recovery time

Primary Symptom: Stomach Issues

Mikayla, a full-time graduate student and marathon runner, had been diagnosed with colitis a few years before finding Ixcela. She turned to Ixcela for help alleviating bloating, cramping, and post-run stomachaches.

Her Ixcela test results revealed:

  • Indole-3-propionic acid below optimal
  • 3-methylxanthine above optimal
  • Xanthine above optimal
  • Uric acid above optimal
  • Total indoxyl sulfate trending above optimal

After following her Ixcela plan for 90 days, Mikayla experienced:

  • 87% decrease in number of days with GI issues
  • 64% decrease in feelings of stress
  • 9% increase in 5K run pace

Primary Symptom: Constipation

Collegiate track-and-field athlete Quincy, struggled with alternating constipation and diarrhea, gas, bloating, and nausea. Her GI distress affected her athletic performance and caused her to miss multiple races each month.

Her Ixcela test results revealed:

  • Indole-3-propionic acid below optimal
  • 3-methylxanthine above optimal
  • Xanthine above optimal

After following her Ixcela plan for 90 days, Quincy experienced:

  • 81% decrease in GI issues (constipation and diarrhea)
  • ~100% decrease in acne

Overcoming constipation and GI distress as a pro triathlete

Sarah struggled with chronic constipation and bloating. With the help of Ixcela’s testing and dietitian support, she was able to normalize her digestion and feel better on a day-in-day-out basis.

FAQ

A metabolite is the by-product of a breakdown process in the body (what’s created after the body metabolizes something). Metabolites can come from the breakdown of consumed food, ingestion of medicines, or tissue breakdown. These metabolites then travel to different areas of the body and can serve various functions including growth, reproduction, and health maintenance.

Ixcela measures gut-health metabolites to provide clues on what may be disrupting your body’s balance, causing GI symptoms, and what specifically to do about it. For example, when indole-3-propionic acid is below optimal levels (which can be one of the key indicators of a leaky gut), we know we need to focus on reducing processed foods, caffeine, and gluten. Or if serotonin is below optimal (often connected to constipation), we know we need to focus on the consumption of Omega 3s, getting at least 30 minutes of sunshine a day, mindfulness, and adequate sleep.

During your one-to-one virtual session with your Ixcela registered dietitian, you’ll be guided on exactly what to do based on your testing results and what feels most realistic for you right now.

While Ixcela cannot cure or treat colitis, Crohn's disease, IBS, or IBD, we have a track record of alleviating symptoms of bloating, cramping, constipation, diarrhea, and nausea for most clients who struggle with GI issues. While we may not be able to alleviate all symptoms, most clients see a substantial difference in their symptoms after working with one of our registered dietitians for 90 days.

Ixcela is not intended to diagnose, treat, cure, or prevent any disease.

No. Food sensitivities are often a symptom of a damaged or imbalanced gut. Ixcela testing and guidance from one of our registered dietitians will help you understand what may be the culprit behind symptoms related to food sensitivities.

No. Insurance does not cover Ixcela programs. If you have questions about FSA/HSA reimbursement eligibility, please speak to your doctor.

More questions? Check out our complete FAQ list.

“My experience with Ixcela was phenomenal. During the time I worked with them, my gut health improved tremendously as I wasn’t as bloated and had much less GI distress overall. The accountability factor was huge as well (shoutout to Shelby!). I’m a coach by trade, but having someone else stay in my ear and coach me up felt really good. Also, Ixcela gives you an incredible amount of resources and education along the way to set up for success post-program.”

Will, Complete Package Program


Health Issues Ixcela Can Help

Athletic Performance

Improve runner’s gut, address stomach issues, recover faster, reduce performance plateaus, fuel smarter

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Pain and Inflammation

Reduce inflammation, alleviate pain, improve recovery time, reduce risk of injuries

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Stress and Anxiety

Address mood swings, reduce stress, ditch burnout, end wired-but-tired cycles, improve mental clarity

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Low Energy
and Fatigue

Improve energy, reduce fatigue, boost motivation, increase stamina, tackle brain fog

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Chronic Conditions

Support hormones, improve autoimmune symptoms, reduce high cholesterol, improve sleep

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