Ixcela Defend

Product Details

Ixcela Defend, a powerful immune-system-boosting blend of antioxidants vitamin C and zinc, is formulated to support Ixcela’s stress marker metabolites, including elevated xanthine, uric acid, and tyrosine.*

Other vitamin C and zinc supplements may cause upset stomach and diarrhea due to excessive amounts of these two nutrients. Ixcela Defend provides an effective dosage that carefully balances vitamin C and zinc so you can give your body the boost it needs without the discomfort.

As with any dietary supplement, consult your health care practitioner before using this product, especially if you are pregnant or nursing, anticipating surgery, taking any medications on a regular basis, or otherwise under medical supervision.

Ixcela supplements are formulated to exclude:

Gluten
Nuts
Preservatives
Corn

Wheat
Fish
Crustacean Shellfish
Added Colors

Soy
GMO
Dairy and Lactose
Eggs

Yeast
Sugars
Artificial Sweeteners

Ixcela supplements are produced at an FDA-registered, GMP-compliant facility and contain no harmful fillers. They are vegetarian and are not tested on animals.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

About Vitamin C

Vitamin C is essential for the growth and repair of tissues and may promote prenatal health, heart health, eye health, and skin elasticity. It is involved in the absorption of iron and the formation of collagen. Vitamin C also assists in the maintenance of cartilage, bones, and teeth.

About Zinc

Zinc supports normal growth and development and plays a role in wound healing, cell division, protein and DNA synthesis, and immune function. Zinc is an essential trace mineral that is naturally present in some foods. Because the body has no specialized zinc storage system, daily intake is required.

Directions for Use

For adults only. Adults take one (1) tablet per day with a meal.

Warning: Keep out of reach of children.

Caution: As with any dietary supplement, consult your health care practitioner before using this product, especially if you are pregnant or nursing, anticipating surgery, taking any medications on a regular basis, or otherwise under medical supervision.

Storage: Keep tightly closed. Store in a dry place and avoid excessive heat.

Citations

Vitamin C

Nishikimi, Morimitsu. “Oxidation of Ascorbic Acid with Superoxide Anion Generated by the Xanthine-Xanthine Oxidase System.” Biochemical and Biophysical Research Communications, vol. 63, no. 2, 1975, pp. 463-468. https://doi.org/10.1016/0006-291X(75)90710-X.
La Du, Bert N., and Zannoni, Vincent G. “The Role of Ascorbic Acid in Tyrosine Metabolism” The New York Academy of Sciences, vol. 92, no. 1, 1961, pp. 175-191. https://doi.org/10.1111/j.1749-6632.1961.tb46117.x.
Huang, Han-Yao, et al. “The Effects of Vitamin C Supplementation on Serum Concentrations of Uric Acid: Results of a Randomized Controlled Trial.” Arthritis & Rheumatism, vol. 52, no. 6, 2005, pp.1843-1847. https://doi.org/10.1002/art.21105.
Gao, Xiang, et al. “Vitamin C Intake and Serum Uric Acid Concentration in Men.” The Journal of Rheumatology, vol. 35, no. 9, 2008, pp. 1853-1858. www.jrheum.org/content/35/9/1853.short.
Choi, Hyon, et al. “Vitamin C Intake and the Risk of Gout in Men.” Archives of Internal Medicine, vol. 169, no. 5, 2009, pp. 502-517. doi: 10.1001/archinternmed.2008.606. https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/414828.
“KEGG Purine Metabolism - Reference Pathway” KEGG PATHWAY. www.kegg.jp/kegg-bin/highlight_pathway?scale=1.0&map=map00230&keyword=Xanthine.

Zinc

Walravens, P. A. “Zinc Metabolism and Its Implications in Clinical Medicine.” The Western Journal of Medicine, vol. 130, no. 2, 1979, pp. 133-142. www.ncbi.nlm.nih.gov/pmc/articles/PMC1238526/.
Powell, Saul R. “Antioxidant Properties of Zinc.” The Journal of Nutrition, vol. 130, no. 5, 2000, pp. 1447-1454. https://doi.org/10.1093/jn/130.5.1447S.
Girotti Albert W., et al. “Inhibitory Effect of Zinc(II) on Free Radical Lipid Peroxidation in Erythrocyte Membranes.” Journal of Free Radicals in Biology & Medicine, vol. 1, no. 5-6, 1985, pp. 395-401. https://doi.org/10.1016/0748-5514(85)90152-7.
Cox, Dennis H. and Harris, Dorothy L. “Reduction of Liver Xanthine Oxidase Activity and Iron Storage Proteins in Rats Fed Excess Zinc.” The Journal of Nutrition, vol. 78, no. 4, 1962, pp. 415-418. https://doi.org/10.1093/jn/78.4.415.
Morita, Yukari, et al. “Identification of Xanthine Dehydrogenase/Xanthine Oxidase as a Rat Paneth Cell Zinc-Binding Protein.” Biochimica Et Biophysica Acta (BBA) - Molecular Cell Research, vol. 1540, no. 1, 2001, pp. 43-49. https://doi.org/10.1016/S0167-4889(01)00118-5.
Fliss, Henry and Ménard, Michel. “Oxidant-Induced Mobilization of Zinc from Metallothionein.” Archives of Biochemistry and Biophysics, vol. 293, no. 1, 1992, pp. 195-199. https://doi.org/10.1016/0003-9861(92)90384-9.
Fischer, P.W., et al. “Effect of Zinc Supplementation on Copper Status in Adult Man.” The American Journal of Clinical Nutrition, vol. 40, no. 4, 1984, pp. 743-746. https://doi.org/10.1093/ajcn/40.4.743.

Vitamin C + Zinc