For a variety of lifestyle-related reasons, the body’s internal biochemistry can be moved from a healthy, balanced state to a state that can lead to chronic disease. These chronic conditions include Alzheimer’s, Parkinson’s, ALS, and diabetes. Additionally, poor internal fitness may cause less severe but more common health issues, such as irritable bowel syndrome, acid reflux, and leaky gut.
The Ixcela approach restores internal health using a sophisticated test and individualized therapy. The Ixcela test identifies imbalances in key small molecules associated with the gut microbiome,and our individualized therapy restores these molecules to their proper levels with a personalized program that includes proprietary supplements, as well as personalized nutrition and fitness plans.
Ixcela has developed a pinprick blood test that looks at the levels of unique small-molecule metabolites shown through experimentation, peer-reviewed literature, and clinical studies to be associated with gut microbiome health. Analysis of the blood spot is performed by proprietary technology, including the Electrochemical Array (CoulArray™) invented by our co-founder Wayne Matson. Ixcela has unique supplements to help regulate specific biomarkers that are not at optimal levels. Thus, Ixcela provides a comprehensive approach to a) determining gut microbiome dysbiosis and b) providing actionable solutions to restoring proper gut microbiome health.
The inspiration for our company name “Ixcela” came from Ixchel—the ancient Mayan goddess of healing and medicine.
Ixcela was co-founded by Drs. Erika Ebbel Angle and Wayne Matson, who were aided by a group of outstanding scientists. Each team member had developed technologies and methods for the study of a range of diseases for diagnosis, predictive diagnostic risk factors, and specification of therapy (personalized medicine).
After deep analysis of the complex biochemical profiles for more than 1,000 compounds in tens of thousands of subjects, it became clear to us that the microbiome (the 6–10,000 species in the gut—the largest organ in the body) was a critical part of the biochemical web distinguishing normal from disease subjects. Understanding these webs could also allow the prediction of therapeutic response. Additionally, the biochemistry of the microbiome had direct links to the function of other organs, including the brain.
This led us beyond the ideas of diagnosis and therapy to the concept of promoting biochemical wellness (“internal health”) through measurement and control of the microbiome with specific, personalized intervention based on testing.